RT Journal Article SR Electronic A1 Lederman, Lynne T1 More Research is Needed to Determine Optimal Therapies for Rectal Cancer JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 22 SP 29 OP 30 DO 10.1177/155989771422020 UL http://mdc.sagepub.com/content/14/22/29.abstract AB Rectal cancer is treated with surgery, radiation therapy (RT), and neoadjuvant and adjuvant chemotherapy (CT); yet, the best way to sequence and combine these modalities is not yet known. This article discusses organ-sparing surgery in rectal cancer, the feasibility of intensifying preoperative RT, as well as preoperative therapy.