RT Journal Article
SR Electronic
A1 Mosley, Mary
T1 Impact of First-Line Therapy on Selection of Second-Line Therapy in FIRE-3 Trial
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 22
SP 16
OP 16
DO 10.1177/155989771422013
UL http://mdc.sagepub.com/content/14/22/16.abstract
AB The influence of the drug combination used for first-line therapy on the selection and duration of the second-line therapy in patients with metastatic colorectal cancer (mCRC) was the objective of a post hoc analysis in the ongoing 5-FU, Folinic Acid and Irinotecan (FOLFIRI) Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment Colorectal Cancer trial [FIRE-3]. This article discusses the effect of first-line therapy on overall survival (OS) and the selection of subsequent treatment, and the effect of second-line therapy on OS [Modest D et al. Ann Oncol. 2014 (abstr O-0018)].