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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/cdn\/css\/http\/css_Xg7z6oCTVgud_Q0huYz9x9iiD5H_2YPSJ5z2ZViSWdY.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EApproximately 7% of patients who undergo cardiac angiography have left main coronary disease (LMCD). This article presents the results of a study that evaluated clinical and demographic characteristics and the outcomes of unprotected LMCA stenting.\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003ECoronary Artery Disease\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003ECardiology Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EInterventional Techniques \u0026amp; Devices\u003C\/li\u003E\u003C\/ul\u003E\u003Cul class=\u0022kwd-group clinical-trial\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003ECoronary Artery Disease\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003ECardiology Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003ECardiology \u0026amp; Cardiovascular Medicine\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EInterventional Techniques \u0026amp; Devices\u003C\/li\u003E\u003C\/ul\u003E\u003Cp id=\u0022p-2\u0022\u003EApproximately 7% of patients who undergo cardiac angiography have left main coronary disease (LMCD). Guidelines as recent as 2012 have recommended surgical revascularization or coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI) [Patel MR et al. \u003Cem\u003EJ Am Coll Cardiol\u003C\/em\u003E 2012]. Some studies evaluating elective PCI with drug-eluting stent (DES) implantation as compared to CABG in unprotected left main coronary artery (LMCA) lesions, however, have reported short- and midterm outcomes that are similar [Chieffo A et al. \u003Cem\u003EJACC Cardiovasc Interv\u003C\/em\u003E 2010; Lee MS et al. \u003Cem\u003EJ Am Coll Cardiol\u003C\/em\u003E 2006].\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003EAntonio Vellegas, MD, Medicina Cardiovascular Asociada, Santo Domingo, Dominican Republic, presented the results of a study that evaluated clinical and demographic characteristics and the outcomes of unprotected LMCA stenting. This was a retrospective, observational case series of 49 patients selected from the Interventional Cardiovascular Department database who received PCI between 2009 and 2013. Outcomes included in-hospital complications, cardiovascular deaths, total deaths, and total days of admission.\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003EThe majority of patients were men (69%) with a mean age of 70.3 \u00b1 3.9 years and a body mass index (BMI) of 26.9 \u00b1 11.1 kg\/m\u003Csup\u003E2\u003C\/sup\u003E. Participants were 85% Hispanic and 15% Caucasian. Most patients (86%) presented with hypertension. Diabetes mellitus was seen in 37% of patients, hypercholesterolemia in 27%, and chronic kidney disease in 6%; 16% were smokers. The following diagnoses were made at admission: stable coronary disease (n = 19), unstable angina (n = 16), myocardial infarction (n = 10), heart failure (n = 3), and cardiogenic shock (n = 1). Radial or femoral vascular access was obtained in all cases. Angiographic assessment denoted isolated left main (LM) disease (11 patients), LM disease plus singlevessel coronary vessel disease (11 patients), and LM disease plus 2 diseased coronary vessels (27 patients). In 81.7% (n = 40) of patients, intravascular ultrasound was used to guide placement of bare metal (n = 2) and sirolimus- (n = 3), everolimus- (n = 21), and\/or zotarolimus (n = 23) eluting stents.\u003C\/p\u003E\u003Cp id=\u0022p-5\u0022\u003EThe mean days of in-hospital observation following PCI was 3.3 \u00b1 2.2 (range, 2 to 7 days). Few patients (6%) experienced in-hospital complications. Major bleeding from the access site, coronary artery dissection and abrupt vessel closure, and coronary artery dissection\/abrupt vessel closure\/acute kidney failure\/death was noted in 1 patient for each event.\u003C\/p\u003E\u003Cp id=\u0022p-6\u0022\u003EDr. Villegas noted that this was a retrospective case series with only in-hospital follow-up. In this series, stenting of unprotected LMCA was associated with a high procedural success and low in-hospital complication rate. He stressed that patient selection for both techniques is fundamental to success and directly affects clinical outcomes.\u003C\/p\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2014 MD Conference Express\u00ae\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/14\/24\/19.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzovze\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}