PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Giugliano, Robert
TI  - Beneficial Effects of Once-Daily Edoxaban in Patients with AF
DP  - 2014 Nov 01
TA  - MD Conference Express
PG  - 11--13
VI  - 14
IP  - 24
4099  - http://mdc.sagepub.com/content/14/24/11.short
4100  - http://mdc.sagepub.com/content/14/24/11.full
AB  - This article reports the results of the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation—TIMI 48 trial [ENGAGE AF-TIMI 48]. This randomized, double-blind, double-dummy trial of 21,105 patients demonstrated the efficacy and safety of a once-daily regimen of the oral anticoagulant edoxaban in treatment of atrial fibrillation (AF). The primary trial results have been published [Giugliano RP et al. N Engl J Med 2013].