RT Journal Article
SR Electronic
A1 Mosley, Mary
T1 POPE-2: No Benefit with Colchicine to Reduce Persistent Postoperative Pericardial Effusion
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 27
SP 15
OP 15
DO 10.1177/155989771427008
UL http://mdc.sagepub.com/content/14/27/15.1.abstract
AB Postoperative pericardial effusion (POPE) is present within the first 7 days after cardiac surgery in 50% to 80% of patients, and the risk for early cardiac tamponade ranges from 0.5% to 1%. There is no drug that can treat this local hemorrhagic complication. The Colchicine Treatment for Post-operative Pericardial Effusion [POPE-2; NCT01266694] was a double-blind, placebo-controlled study to evaluate whether COL could reduce the volume of POPE.