PT - JOURNAL ARTICLE AU - Mosley, Mary ED - Meurin, Philippe TI - POPE-2: No Benefit with Colchicine to Reduce Persistent Postoperative Pericardial Effusion DP - 2014 Nov 01 TA - MD Conference Express PG - 15--15 VI - 14 IP - 27 4099 - http://mdc.sagepub.com/content/14/27/15.1.short 4100 - http://mdc.sagepub.com/content/14/27/15.1.full AB - Postoperative pericardial effusion (POPE) is present within the first 7 days after cardiac surgery in 50% to 80% of patients, and the risk for early cardiac tamponade ranges from 0.5% to 1%. There is no drug that can treat this local hemorrhagic complication. The Colchicine Treatment for Post-operative Pericardial Effusion [POPE-2; NCT01266694] was a double-blind, placebo-controlled study to evaluate whether COL could reduce the volume of POPE.