PT  - JOURNAL ARTICLE
AU  - Mosley, Mary
ED  - Zannad, Faiez
TI  - NECTAR-HF: Cardiac Remodeling Not Reduced with VNS
DP  - 2014 Nov 01
TA  - MD Conference Express
PG  - 12--13
VI  - 14
IP  - 27
4099  - http://mdc.sagepub.com/content/14/27/12.short
4100  - http://mdc.sagepub.com/content/14/27/12.full
AB  - Vagal nerve stimulation (VNS) did not reduce the primary end point of cardiac remodeling at 6 months in patients who had heart failure (HF) with reduced ejection fraction in the first sham-controlled, double-blind clinical trial to evaluate this approach. The Neutral Cardiac Therapy for Heart Failure study [NECTAR-HF; Zannad F et al. Eur Heart J. 2014] sought to determine whether an implanted VNS system would reset the altered autonomic nervous system balance found in HF. The 6-month data were presented, and follow-up will continue to 18 months.