RT Journal Article SR Electronic A1 Vinall, Maria T1 Effects of PDE-5 Inhibition in Patients with T2DM JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 32 SP 25 OP 25 DO 10.1177/155989771432018 UL http://mdc.sagepub.com/content/14/32/25.abstract AB Patients with obesity, insulin resistance, and T2DM have postprandial hyperglycemia and impaired postprandial microvascular response. This article reviews results from the Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes study [NCT01238224], which investigated the effect of tadalafil on postprandial hyperglycemia and circulating levels of proinflammatory markers in patients with T2DM after a mixed meal.