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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/advagg_css\/css__ce2QY63WIanKyr8eSq7eavr1XQRRmFD6ZSmwpyJi8lM__zXwFqpqmxrZOXXcd_TpBQpjuELbmIP9wBR5UuTDWAO4__YJWWMMdfCJuAFm5cUEp88OsodhO3ZA-2lzRfoBsSlk4.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EUp to 2 million patients per year require treatment for plantar fasciitis, with risk factors including prolonged weight-bearing activity, inappropriate shoe wear, greater body weight, and medical comorbidities. This article discusses data from the Treatment of Plantar Fasciitis With Xeomin study [\u003Ca class=\u0022external-ref external-ref-type-clintrialgov\u0022 href=\u0022\/lookup\/external-ref?link_type=CLINTRIALGOV\u0026amp;access_num=NCT01678001\u0026amp;atom=%2Fspmdc%2F14%2F34%2F12.atom\u0022\u003ENCT01678001\u003C\/a\u003E], which evaluated long-term outcomes of patients with plantar fasciitis treated with incobotulinum toxin A.\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003EFoot \u0026amp; Ankle Conditions\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EOrthopaedics Clinical Trials\u003C\/li\u003E\u003C\/ul\u003E\u003Cul class=\u0022kwd-group clinical-trial\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003EFoot \u0026amp; Ankle Conditions\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EOrthopaedics Clinical Trials\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EOrthopaedics\u003C\/li\u003E\u003C\/ul\u003E\u003Cp id=\u0022p-2\u0022\u003ETreatment of plantar fasciitis with incobotulinum toxin A resulted in improved functional and pain outcomes and increased patient satisfaction as compared with placebo. Jamal Ahmad, MD, Rothman Institute, Philadelphia, Pennsylvania, USA, presented data from the Treatment of Plantar Fasciitis With Xeomin study [\u003Ca class=\u0022external-ref external-ref-type-clintrialgov\u0022 href=\u0022\/lookup\/external-ref?link_type=CLINTRIALGOV\u0026amp;access_num=NCT01678001\u0026amp;atom=%2Fspmdc%2F14%2F34%2F12.atom\u0022\u003ENCT01678001\u003C\/a\u003E].\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003EUp to 2 million patients per year require treatment for plantar fasciitis, with risk factors including prolonged weight-bearing activity, inappropriate shoe wear, greater body weight, and medical comorbidities. Botulinum toxin has been studied for the treatment of plantar fasciitis in several short-term prospective studies, demonstrating symptom improvement in up to 90% of patients at 3- and 6-month follow-up [Diaz-Llopis IV et al. \u003Cem\u003EClin Rehabil\u003C\/em\u003E. 2013; Placzek R et al. \u003Cem\u003EClin J Pain\u003C\/em\u003E. 2006]. The purpose of this study was to evaluate long-term outcomes of patients with plantar fasciitis treated with incobotulinum toxin A.\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003EIn this prospective double-blind study, 28 patients with plantar fasciitis who had unsuccessful nonsurgical treatment were randomly assigned to receive a 1-cc injection of 100 U of botulinum toxin or placebo. A board certified neurologist placed the injection at the flexor digitorum brevis muscle, which is continuous with the plantar fascia. Postinjection, patients completed physical therapy, including plantar fascial and Achilles stretching. Clinical end points included Foot and Ankle Ability Measure, visual analog scale, and patient satisfaction.\u003C\/p\u003E\u003Cp id=\u0022p-5\u0022\u003EAt 1-year follow-up, patients who received botulinum toxin had a significantly higher mean Foot and Ankle Ability Measure score of 73.8, compared with 40.9 in placebo-treated patients (\u003Cem\u003EP\u003C\/em\u003E = .01). In addition, the mean visual analog scale score, a measure of pain, was significantly lower in the botulinum toxin arm, with a score of 3.6 out of 10, compared with 7.9 in the placebo arm (\u003Cem\u003EP\u003C\/em\u003E = .01). Approximately 86% of patients in the botulinum toxin arm and 36% of patients in the placebo arm reported symptom improvement, with about 29% in the botulinum toxin arm indicating that they had achieved complete relief. In the botulinum toxin group, about 14% of patients experienced no change in symptoms, although none received surgery. In the placebo arm, about 64% of patients experienced no change in symptoms, with 2 patients undergoing surgery at 6 months.\u003C\/p\u003E\u003Cp id=\u0022p-6\u0022\u003EPatient satisfaction was greater in the botulinum toxin arm, with about 29% and 50% reporting that they had excellent and good satisfaction, respectively, compared with 0% and 7% in the placebo arm (\u003Ca id=\u0022xref-table-wrap-1-1\u0022 class=\u0022xref-table\u0022 href=\u0022#T1\u0022\u003ETable 1\u003C\/a\u003E). There were no reports of injection-related complications in either study arm.\u003C\/p\u003E\u003Cdiv id=\u0022T1\u0022 class=\u0022table pos-float\u0022\u003E\u003Cdiv class=\u0022table-inline\u0022\u003E\u003Cdiv class=\u0022callout\u0022\u003E\u003Cspan\u003EView this table:\u003C\/span\u003E\u003Cul class=\u0022callout-links\u0022\u003E\u003Cli class=\u00220 first\u0022\u003E\u003Ca href=\u0022\/\u0022 class=\u0022table-expand-inline\u0022 data-table-url=\u0022\/highwire\/markup\/12067\/expansion?postprocessors=highwire_figures%2Chighwire_math%2Chighwire_inline_linked_media%2Chighwire_embed\u0026amp;table-expand-inline=1\u0022 html=\u00221\u0022 fragment=\u0022#\u0022 external=\u00221\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView inline\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00221\u0022\u003E\u003Ca href=\u0022\/highwire\/markup\/12067\/expansion?width=1000\u0026amp;height=500\u0026amp;iframe=true\u0026amp;postprocessors=highwire_figures%2Chighwire_math%2Chighwire_inline_linked_media\u0022 class=\u0022colorbox colorbox-load table-expand-popup\u0022 rel=\u0022gallery-fragment-tables\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView popup\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00222 last\u0022\u003E\u003Ca href=\u0022\/highwire\/powerpoint\/12067\u0022 class=\u0022highwire-figure-link highwire-figure-link-ppt\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload powerpoint\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv class=\u0022table-caption\u0022\u003E\u003Cspan class=\u0022table-label\u0022\u003ETable 1.\u003C\/span\u003E \n            \u003Cp id=\u0022p-7\u0022 class=\u0022first-child\u0022\u003EEffect of Botulinum Toxin on Patient Satisfaction, No. (%)\u003C\/p\u003E\n         \u003Cdiv class=\u0022sb-div caption-clear\u0022\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cp id=\u0022p-9\u0022\u003EIn conclusion, Dr Ahmad stated that, in his opinion, the data from this study indicate that treatment of plantar fasciitis with botulinum toxin resulted in greater functional scores and patient satisfaction, as well as lower pain scores, when compared with placebo. However, the study was limited by a small sample size, potential differences in physical therapy regimens, and potential use of patient-directed treatments.\u003C\/p\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2014 MD Conference Express\u00ae\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/14\/34\/12.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzoqw1\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_tables.js?nzoqw1\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}