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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/cdn\/css\/http\/css_Xg7z6oCTVgud_Q0huYz9x9iiD5H_2YPSJ5z2ZViSWdY.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cdiv class=\u0022section abstract\u0022 id=\u0022abstract-1\u0022\u003E\u003Ch2\u003ESummary\u003C\/h2\u003E\n            \u003Cp id=\u0022p-1\u0022\u003EPatients with psoriasis are at an increased risk of developing multiple comorbidities, including psoriatic arthritis (PsA), cardiovascular disease, diabetes mellitus, and cancer. This article discusses the practical aspects of diagnosing and managing patients, cardiometabolic risk assessment in patients with psoriasis, as well as systemic comorbidities with psoriasis.\u003C\/p\u003E\n         \u003C\/div\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003ESkin Diseases\u003C\/li\u003E\u003C\/ul\u003E\u003Cul class=\u0022kwd-group clinical-trial\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003ESkin Diseases\u003C\/li\u003E\u003Cli class=\u0022kwd\u0022\u003EDermatology\u003C\/li\u003E\u003C\/ul\u003E\u003Cp id=\u0022p-2\u0022\u003EPatients with psoriasis are at an increased risk of developing multiple comorbidities, including psoriatic arthritis (PsA), cardiovascular disease, diabetes mellitus, and cancer. Wolf-Henning Boehncke, MD, MA, University of Geneva, Geneva, Switzerland, discussed the practical aspects of diagnosing and managing patients with psoriasis for dermatologists.\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003EPsoriasis is associated with an increased risk of multiple comorbidities, including obesity, anxiety and depression, diabetes mellitus, and lymphoma, as well as PsA [Daud\u00e9n E et al. \u003Cem\u003EActas Dermosifiliogr\u003C\/em\u003E. 2012]. Importantly, up to 42% of patients with psoriasis have PsA, and 75% of patients develop PsA after their diagnosis of plaque psoriasis; therefore, dermatologists serve as sentinels for early detection of the disease. Currently used questionnaires, the Psoriasis Epidemiology Screening Tool, Psoriatic Arthritis Screening and Evaluation, and Toronto Psoriatic Arthritis Screening, may have limited sensitivity for the identification of inflammatory joint disease [Haroon M et al. \u003Cem\u003EAnn Rheum Dis.\u003C\/em\u003E 2013]. Until better screening methods are developed, however, Prof Boehncke suggested that dermatologists continue using screening questionnaires, as well as asking about and examining the patient for tender or swollen joints and back pain. The early diagnosis of PsA is important because a delay of even 6 months is associated with poor functional and radiographic outcomes [Haroon M et al. \u003Cem\u003EAnn Rheum Dis.\u003C\/em\u003E 2014].\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003EThe diagnosis of PsA is important because it affects treatment decisions and generally indicates a need to refer the patient to a rheumatologist. Available treatments include nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and anti-tumor necrosis factor (TNF) therapies. NSAIDs and the currently used DMARDs do not, however, prevent radiographic progression of PsA, whereas anti-TNF therapies, including adalimumab [Mease PJ et al. \u003Cem\u003EAnn Rheum Dis.\u003C\/em\u003E 2009], etanercept, and infliximab, can halt progression (\u003Ca id=\u0022xref-fig-1-1\u0022 class=\u0022xref-fig\u0022 href=\u0022#F1\u0022\u003EFigure 1\u003C\/a\u003E).\u003C\/p\u003E\u003Cdiv id=\u0022F1\u0022 class=\u0022fig pos-float  odd\u0022\u003E\u003Cdiv class=\u0022highwire-figure\u0022\u003E\u003Cdiv class=\u0022fig-inline-img-wrapper\u0022\u003E\u003Cdiv class=\u0022fig-inline-img\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F1.large.jpg?width=800\u0026amp;height=600\u0026amp;carousel=1\u0022 title=\u0022Anti-Tumor Necrosis Factor Therapies Halt Radiographic Progression of Psoriatic Arthritis\u0022 class=\u0022fragment-images colorbox-load\u0022 rel=\u0022gallery-fragment-images-33107412\u0022 data-figure-caption=\u0022Anti-Tumor Necrosis Factor Therapies Halt Radiographic Progression of Psoriatic Arthritis\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003E\u003Cimg class=\u0022fragment-image\u0022 alt=\u0022Figure 1.\u0022 src=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F1.medium.gif\u0022\/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cul class=\u0022highwire-figure-links inline\u0022\u003E\u003Cli class=\u00220 first\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F1.large.jpg?download=true\u0022 class=\u0022highwire-figure-link highwire-figure-link-download\u0022 title=\u0022Download Figure 1.\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload figure\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00221\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F1.large.jpg\u0022 class=\u0022highwire-figure-link highwire-figure-link-newtab\u0022 target=\u0022_blank\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EOpen in new tab\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00222 last\u0022\u003E\u003Ca href=\u0022\/highwire\/powerpoint\/12115\u0022 class=\u0022highwire-figure-link highwire-figure-link-ppt\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload powerpoint\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003Cdiv class=\u0022fig-caption attrib\u0022\u003E\u003Cspan class=\u0022fig-label\u0022\u003EFigure 1.\u003C\/span\u003E \n            \u003Cp id=\u0022p-5\u0022 class=\u0022first-child\u0022\u003EAnti-Tumor Necrosis Factor Therapies Halt Radiographic Progression of Psoriatic Arthritis\u003C\/p\u003E\n         \u003Cq class=\u0022attrib\u0022 id=\u0022attrib-1\u0022\u003EmTSS, modified total Sharp score.\u003C\/q\u003E\u003Cq class=\u0022attrib\u0022 id=\u0022attrib-2\u0022\u003EReproduced with permission from WH Boehncke, MD, MA.\u003C\/q\u003E\u003Cdiv class=\u0022sb-div caption-clear\u0022\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cp id=\u0022p-6\u0022\u003ETreatment method can also affect outcomes, because a treat-to-target strategy resulted in nearly 100% of patients who achieved minimal disease activity (MDA) experiencing no radiologic progression, compared with about 35% and 42% of those who did not achieve MDA experiencing radiographic progression at weeks 52 and 104 (\u003Cem\u003EP\u003C\/em\u003E = .012) [Coates LC, Helliwell PS. \u003Cem\u003EArthritis Care Res (Hoboken)\u003C\/em\u003E. 2010].\u003C\/p\u003E\u003Cp id=\u0022p-7\u0022\u003ENehal Mehta, MD, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA, outlined the role of cardiometabolic risk assessment in patients with psoriasis. Cardiometabolic disease encompasses the presence of any disease of the vasculature, glucose metabolism, and adipose dysfunction such as obesity, and lipoprotein metabolism. Typically, cardiovascular risk assessment is performed using the Framingham risk score, which predicts the 10-year risk of major adverse cardiovascular events (MACEs) [Wilson PWF et al. \u003Cem\u003ECirculation\u003C\/em\u003E. 1998]. The Framingham risk score, however, does not account for important risk factors such as genetic predisposition, hemostatic or thrombotic disease, behavioral or lifestyle factors other than smoking, and inflammatory disease.\u003C\/p\u003E\u003Cp id=\u0022p-8\u0022\u003EThe presence of inflammatory disease, which includes psoriasis, is a risk factor for cardiovascular disease; high-sensitivity C-reactive protein is associated with a relative risk of \u0026gt; 4.0 for future cardiovascular events [Libby P et al. \u003Cem\u003EAm J Med.\u003C\/em\u003E 2004]. In addition, psoriasis is associated with vascular inflammation [Mehta NN et al. \u003Cem\u003EArch Dermatol\u003C\/em\u003E. 2011]. Patients with severe psoriasis have a 50% increased risk of mortality related to cardiovascular disease and are at an increased risk of developing myocardial infarction and stroke (\u003Ca id=\u0022xref-table-wrap-1-1\u0022 class=\u0022xref-table\u0022 href=\u0022#T1\u0022\u003ETable 1\u003C\/a\u003E) [Maradit-Kremers H et al. \u003Cem\u003EInt J Dermatol\u003C\/em\u003E. 2013; Mehta NN et al. \u003Cem\u003EAm J Med.\u003C\/em\u003E 2011; Mehta NN et al. \u003Cem\u003EEur Heart J.\u003C\/em\u003E 2010; Gelfand JM et al. \u003Cem\u003EJ Invest Dermatol\u003C\/em\u003E. 2009; Gelfand JM et al. \u003Cem\u003EJAMA\u003C\/em\u003E. 2006].\u003C\/p\u003E\u003Cdiv id=\u0022T1\u0022 class=\u0022table pos-float\u0022\u003E\u003Cdiv class=\u0022table-inline\u0022\u003E\u003Cdiv class=\u0022callout\u0022\u003E\u003Cspan\u003EView this table:\u003C\/span\u003E\u003Cul class=\u0022callout-links\u0022\u003E\u003Cli class=\u00220 first\u0022\u003E\u003Ca href=\u0022\/\u0022 class=\u0022table-expand-inline\u0022 data-table-url=\u0022\/highwire\/markup\/12118\/expansion?postprocessors=highwire_figures%2Chighwire_math%2Chighwire_inline_linked_media%2Chighwire_embed\u0026amp;table-expand-inline=1\u0022 html=\u00221\u0022 fragment=\u0022#\u0022 external=\u00221\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView inline\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00221\u0022\u003E\u003Ca href=\u0022\/highwire\/markup\/12118\/expansion?width=1000\u0026amp;height=500\u0026amp;iframe=true\u0026amp;postprocessors=highwire_figures%2Chighwire_math%2Chighwire_inline_linked_media\u0022 class=\u0022colorbox colorbox-load table-expand-popup\u0022 rel=\u0022gallery-fragment-tables\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView popup\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00222 last\u0022\u003E\u003Ca href=\u0022\/highwire\/powerpoint\/12118\u0022 class=\u0022highwire-figure-link highwire-figure-link-ppt\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload powerpoint\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cdiv class=\u0022table-caption\u0022\u003E\u003Cspan class=\u0022table-label\u0022\u003ETable 1.\u003C\/span\u003E \n            \u003Cp id=\u0022p-9\u0022 class=\u0022first-child\u0022\u003EEffect of Severe Psoriasis on Risk of Cardiovascular Disease\u003C\/p\u003E\n         \u003Cdiv class=\u0022sb-div caption-clear\u0022\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cp id=\u0022p-10\u0022\u003EDr Mehta recommends calculating the risk of cardiovascular disease associated with severe psoriasis, by multiplying the adjusted hazard ratio of cardiovascular disease for severe psoriasis (1.531297) by the baseline incidence (0.0115902 events per year), which equals the adjusted incidence rate for severe psoriasis (0.017748) [Mehta NN et al. \u003Cem\u003EAm J Med.\u003C\/em\u003E 2011]. Then, the baseline incidence (0.0115902) can be subtracted from the adjusted incidence rate (0.017748) to equal the excess rate per year (0.006158). The excess rate multiplied by 10 years results in a 10-year risk of 6.2%. Therefore, the Framingham risk score can be adjusted to include the risk of cardiovascular disease associated with psoriasis [Mehta NN et al. \u003Cem\u003EJ Am Acad Dermatol\u003C\/em\u003E. 2012]. There is growing support for the idea that all patients with psoriasis should be screened by any health care provider for cardiovascular risk factors beginning at age 18 years and continued every 5 years.\u003C\/p\u003E\u003Cp id=\u0022p-11\u0022\u003EDiamant Tha\u00e7i, MD, University of L\u00fcbeck, L\u00fcbeck, Germany, discussed the association of other systemic comorbidities with psoriasis. Psoriasis has a reported association with Crohn disease [Skroza N et al. \u003Cem\u003EBiomed Res Int.\u003C\/em\u003E 2013]. In addition, patients with psoriasis are at a greater risk of developing celiac disease (odds ratio, 2.36; 95% CI, 1.15 to 4.83) [Bhatia BK et al. \u003Cem\u003EJ Am Acad Dermatol\u003C\/em\u003E. 2014].\u003C\/p\u003E\u003Cp id=\u0022p-12\u0022\u003EThe risk of developing diabetes is also higher in patients with psoriasis [Armstrong AW et al. \u003Cem\u003EJAMA Dermatol\u003C\/em\u003E. 2013], and the Psoriasis Area and Severity Index score is associated with insulin resistance [Boehncke S et al. \u003Cem\u003EBr J Dermatol\u003C\/em\u003E. 2007]. Furthermore, the greater the severity of psoriasis, the shorter the time to the occurrence of diabetes (\u003Ca id=\u0022xref-fig-2-1\u0022 class=\u0022xref-fig\u0022 href=\u0022#F2\u0022\u003EFigure 2\u003C\/a\u003E) [Lee MS et al. \u003Cem\u003EJ Am Acad Dermatol\u003C\/em\u003E. 2014]. Patients with psoriasis who also have dyslipidemia, hypertension, or Cushing disease may be at an even greater risk of developing diabetes. In addition, treatment of psoriasis with psoralen plus ultraviolet A treatment also appears to increase the risk of diabetes [Lee MS et al. \u003Cem\u003EJ Am Acad Dermatol\u003C\/em\u003E. 2014].\u003C\/p\u003E\u003Cdiv id=\u0022F2\u0022 class=\u0022fig pos-float  odd\u0022\u003E\u003Cdiv class=\u0022highwire-figure\u0022\u003E\u003Cdiv class=\u0022fig-inline-img-wrapper\u0022\u003E\u003Cdiv class=\u0022fig-inline-img\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F2.large.jpg?width=800\u0026amp;height=600\u0026amp;carousel=1\u0022 title=\u0022Association of Psoriasis Severity and Diabetes Mellitus\u0022 class=\u0022fragment-images colorbox-load\u0022 rel=\u0022gallery-fragment-images-33107412\u0022 data-figure-caption=\u0022Association of Psoriasis Severity and Diabetes Mellitus\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003E\u003Cimg class=\u0022fragment-image\u0022 alt=\u0022Figure 2.\u0022 src=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F2.medium.gif\u0022\/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cul class=\u0022highwire-figure-links inline\u0022\u003E\u003Cli class=\u00220 first\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F2.large.jpg?download=true\u0022 class=\u0022highwire-figure-link highwire-figure-link-download\u0022 title=\u0022Download Figure 2.\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload figure\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00221\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F2.large.jpg\u0022 class=\u0022highwire-figure-link highwire-figure-link-newtab\u0022 target=\u0022_blank\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EOpen in new tab\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00222 last\u0022\u003E\u003Ca href=\u0022\/highwire\/powerpoint\/12116\u0022 class=\u0022highwire-figure-link highwire-figure-link-ppt\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload powerpoint\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003Cdiv class=\u0022fig-caption attrib\u0022\u003E\u003Cspan class=\u0022fig-label\u0022\u003EFigure 2.\u003C\/span\u003E \n            \u003Cp id=\u0022p-13\u0022 class=\u0022first-child\u0022\u003EAssociation of Psoriasis Severity and Diabetes Mellitus\u003C\/p\u003E\n         \u003Cq class=\u0022attrib\u0022 id=\u0022attrib-3\u0022\u003ERepublished with permission of American Academy of Dermatology, from \u003Cem\u003EJ Am Acad Dermatol\u003C\/em\u003E. Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: A nationwide population-based cohort study. Lee MS et al. 70(4):691\u2013698. 2014; permission conveyed through Copyright Clearance Center, Inc.\u003C\/q\u003E\u003Cdiv class=\u0022sb-div caption-clear\u0022\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cp id=\u0022p-14\u0022\u003ESleep disturbance is also associated with psoriasis, and treatment with etanercept has been reported to result in improved sleep [Tha\u00e7i D et al. \u003Cem\u003EJ Eur Acad Dermatol Venereol\u003C\/em\u003E. 2014]. A subanalysis of the PRISTINE study found that patients with moderate to severe psoriasis were more likely to suffer from symptoms of sleep apnea, sleep disturbance, and somnolence compared with the general population. Treatment with etanercept improved these symptoms during a period of 24 weeks.\u003C\/p\u003E\u003Cp id=\u0022p-15\u0022\u003EData suggest that an elevated risk of cancers, such as those of the colon, bladder, kidney, pharynx, larynx, esophagus, stomach, liver, vulva, breast, and pancreas, as well as leukemia, non-Hodgkin lymphoma, and non-melanoma skin cancers, may be associated with psoriasis, with risk profiles differing for different tumor types [Beyaert R et al. \u003Cem\u003EMol Cancer\u003C\/em\u003E. 2013].\u003C\/p\u003E\u003Cp id=\u0022p-16\u0022\u003EIn conclusion, psoriasis is more than just a disease that affects the skin; psoriasis is associated with serious comorbidities, including inflammatory arthritis, cardiovascular disease, diabetes mellitus, and possibly some cancers. It is important that dermatologists screen for potential comorbidities to initiate early treatment and appropriate referral.\u003C\/p\u003E\u003Cdiv id=\u0022F3\u0022 class=\u0022fig pos-float  odd\u0022\u003E\u003Cdiv class=\u0022highwire-figure\u0022\u003E\u003Cdiv class=\u0022fig-inline-img-wrapper\u0022\u003E\u003Cdiv class=\u0022fig-inline-img\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F3.large.jpg?width=800\u0026amp;height=600\u0026amp;carousel=1\u0022 title=\u0022The editors would like to thank the many members of the 2014 European Academy of Dermatology and Venereology presenting faculty who generously gave their time to ensure the accuracy and quality of the articles in this publication.\u0022 class=\u0022fragment-images colorbox-load\u0022 rel=\u0022gallery-fragment-images-33107412\u0022 data-figure-caption=\u0022The editors would like to thank the many members of the 2014 European Academy of Dermatology and Venereology presenting faculty who generously gave their time to ensure the accuracy and quality of the articles in this publication.\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003E\u003Cimg class=\u0022fragment-image\u0022 alt=\u0022Figure3\u0022 src=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F3.medium.gif\u0022\/\u003E\u003C\/a\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cul class=\u0022highwire-figure-links inline\u0022\u003E\u003Cli class=\u00220 first\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F3.large.jpg?download=true\u0022 class=\u0022highwire-figure-link highwire-figure-link-download\u0022 title=\u0022Download Figure3\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload figure\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00221\u0022\u003E\u003Ca href=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/content\/spmdc\/14\/37\/17\/F3.large.jpg\u0022 class=\u0022highwire-figure-link highwire-figure-link-newtab\u0022 target=\u0022_blank\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EOpen in new tab\u003C\/a\u003E\u003C\/li\u003E\u003Cli class=\u00222 last\u0022\u003E\u003Ca href=\u0022\/highwire\/powerpoint\/12117\u0022 class=\u0022highwire-figure-link highwire-figure-link-ppt\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EDownload powerpoint\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003C\/div\u003E\u003Cdiv class=\u0022fig-caption\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\n            \u003Cp id=\u0022p-17\u0022 class=\u0022first-child\u0022\u003EThe editors would like to thank the many members of the 2014 European Academy of Dermatology and Venereology presenting faculty who generously gave their time to ensure the accuracy and quality of the articles in this publication.\u003C\/p\u003E\n         \u003Cdiv class=\u0022sb-div caption-clear\u0022\u003E\u003C\/div\u003E\u003C\/div\u003E\u003C\/div\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2014 MD Conference Express\u00ae\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Ca href=\u0022http:\/\/mdc.sagepub.com\/content\/14\/37\/17.abstract\u0022 class=\u0022hw-link hw-link-article-abstract\u0022 data-icon-position=\u0022\u0022 data-hide-link-title=\u00220\u0022\u003EView Summary\u003C\/a\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_figures.js?nzop9p\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzop9p\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_tables.js?nzop9p\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}