<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rizzo, Toni</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Valenzuela, Fernando</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Health-Related QOL Improved with Tofacitinib in Patients with Psoriasis</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014-11-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">9-10</style></pages><abstract><style  face="normal" font="default" size="100%">Moderate to severe plaque psoriasis has both physical and psychological effects, leading to major impairment of health-related quality of life. Tofacitinib, an oral Janus kinase inhibitor, was found to be effective in A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study of the Efficacy and Safety Comparing CP- 690,550 and Etanercept in Subjects With Moderate to Severe Chronic Plaque Psoriasis [NCT01241591]. The objective of this analysis of the tofacitinib phase 3 trial was to assess the effects of tofacitinib (5 and 10 mg, BID) versus etanercept or placebo on patient-reported outcomes.</style></abstract><number><style face="normal" font="default" size="100%">37</style></number><volume><style face="normal" font="default" size="100%">14</style></volume></record></records></xml>