PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Kottilil, Shyam
TI  - Interferon- and RBV-Free Treatment with LDV and SOF is Efficacious in Patients Coinfected with HCV and HIV
DP  - 2014  01
TA  - MD Conference Express
PG  - 25--25
VI  - 14
IP  - 48
4099  - http://mdc.sagepub.com/content/14/48/25.short
4100  - http://mdc.sagepub.com/content/14/48/25.full
AB  - Patients coinfected with hepatitis virus C (HCV) and HIV tend to respond poorly to interferon-based therapy and are at higher risk of treatment-related toxicities and adverse events. Treatment options are limited. There is some evidence that interferon-free therapy may work as well in patients who are HIV positive or negative. This article discusses a phase 2 study looking at the treatment option of sofosbuvir and the HCV NS5A inhibitor ledipasvir.