RT Journal Article
SR Electronic
A1 Hoyle, Brian
T1 Interferon- and RBV-Free Treatment with LDV and SOF is Efficacious in Patients Coinfected with HCV and HIV
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 48
SP 25
OP 25
DO 10.1177/155989771448019
UL http://mdc.sagepub.com/content/14/48/25.abstract
AB Patients coinfected with hepatitis virus C (HCV) and HIV tend to respond poorly to interferon-based therapy and are at higher risk of treatment-related toxicities and adverse events. Treatment options are limited. There is some evidence that interferon-free therapy may work as well in patients who are HIV positive or negative. This article discusses a phase 2 study looking at the treatment option of sofosbuvir and the HCV NS5A inhibitor ledipasvir.