PT - JOURNAL ARTICLE AU - Rizzo, Toni ED - Gane, Edward J. TI - Rapid Sustained HCV Viral Load Reductions Achieved with ACH-3102 Plus SOF DP - 2014 01 TA - MD Conference Express PG - 9--10 VI - 14 IP - 48 4099 - http://mdc.sagepub.com/content/14/48/9.short 4100 - http://mdc.sagepub.com/content/14/48/9.full AB - ACH-3102 is a second-generation hepatitis C virus (HCV) nonstructural 5A (NS5A) protein inhibitor with potent activity against HCV genotype (GT)-1 through GT-6. An ongoing phase 2 open-label study evaluated the safety and efficacy of 8 and 6 weeks of ACH-3102 plus sofosbuvir therapy in treatment-naïve patients with chronic HCV GT-1 infection, as discussed in this article.