Use of Molecular Biology for Identifying Benign Hepatocellular Tumors Leads to More Personalized Medicine

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Figures

  • Figure 1.

    Algorithm for the Diagnoses and Treatment of Hepatocellular Adenoma

    CRP, C-reactive protein; GS, glutamine synthetase; HCA, hepatocellular adenoma; HCC, hepatocellular carcinoma; HNF1A, hepatocyte nuclear factor 1 alpha; IHC, immunohistochemistry; LFABP, liver-type fatty acid-binding protein; MRI, magnetic resonance imaging; OC, oral contraception; SAA, serum amyloid A.Adapted with permission of AGA Institute, from Nault JC et al. Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care. Gastroenterology. 2013;144:888–902. Copyright © 2013. Permission conveyed through Copyright Clearance Center, Inc.
  • Figure 2.

    Using the Genotype-Phenotype Hepatocellular Adenoma Classification for Personalized Treatment

    CRP, C-reactive protein; HCA, hepatocellular adenoma; HCC, hepatocellular carcinoma; HNF1A, hepatocyte nuclear factor 1 alpha; LFABP, liver-type fatty acid-binding protein 1; MODY3, maturity-onset diabetes of the young type 3; NT, normal tissue; SAA, serum amyloid A; T2W, T2-weighted.Adapted with permission of AGA Institute, from Nault JC et al. Hepatocellular Benign Tumors—From Molecular Classification to Personalized Clinical Care. Gastroenterology. 2013;144:888–113; 902. Copyright © 2013. Permission conveyed through Copyright Clearance Center, Inc.