PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Baeten, Dominique TI - MEASURE 1: Secukinumab an Effective Treatment for Active AS DP - 2014 01 TA - MD Conference Express PG - 18--18 VI - 14 IP - 51 4099 - http://mdc.sagepub.com/content/14/51/18.short 4100 - http://mdc.sagepub.com/content/14/51/18.full AB - Secukinumab, a high-affinity fully human monoclonal immunoglobulin G 1K antibody that selectively binds to and inhibits interleukin-17A, improves the signs and symptoms of active ankylosing spondylitis (AS). This article presents the results of the 16-Week Efficacy and 2-Year Long-term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis trial [MEASURE 1; NCT01358175], which evaluated intravenous loading and maintenance dosing of secukinumab.