PT  - JOURNAL ARTICLE
AU  - Mosley, Mary
ED  - Kato, Eri Toda
TI  - ENGAGE AF-TIMI 48: Edoxaban Safe and Effective in Elderly Patients with AF
DP  - 2014  01
TA  - MD Conference Express
PG  - 25--26
VI  - 14
IP  - 52
4099  - http://mdc.sagepub.com/content/14/52/25.short
4100  - http://mdc.sagepub.com/content/14/52/25.full
AB  - Atrial fibrillation (AF) becomes more common with increasing age. Data from an unpublished new analysis of the Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation [ENGAGE AF-TIMI 48] support edoxaban as an alternative treatment to warfarin in elderly patients who require anticoagulation therapy. This article discusses a prespecified analysis that evaluated the association of age on study outcomes and the efficacy and safety of edoxaban relative to warfarin in the elderly with AF.