PT - JOURNAL ARTICLE AU - Hitt Nichols, Emma ED - Frost, Charles TI - 4F-PCC Reverses Apixaban Anticoagulation in Healthy Volunteers DP - 2014 01 TA - MD Conference Express PG - 21--21 VI - 14 IP - 55 4099 - http://mdc.sagepub.com/content/14/55/21.short 4100 - http://mdc.sagepub.com/content/14/55/21.full AB - Apixaban anticoagulation was rapidly reversed by 4 factor–prothrombin complex concentrate in healthy volunteers, as measured by endogenous thrombin potential. Adverse events occurred more frequently after 4 factor–prothrombin complex concentrate compared with placebo, most commonly nasopharyngitis and abdominal pain. However, there were no reports of thrombosis or other serious adverse events.