RT Journal Article
SR Electronic
A1 Hitt Nichols, Emma
T1 4F-PCC Reverses Apixaban Anticoagulation in Healthy Volunteers
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 55
SP 21
OP 21
DO 10.1177/1559897715570602
UL http://mdc.sagepub.com/content/14/55/21.abstract
AB Apixaban anticoagulation was rapidly reversed by 4 factor–prothrombin complex concentrate in healthy volunteers, as measured by endogenous thrombin potential. Adverse events occurred more frequently after 4 factor–prothrombin complex concentrate compared with placebo, most commonly nasopharyngitis and abdominal pain. However, there were no reports of thrombosis or other serious adverse events.