RT Journal Article SR Electronic A1 Lederman, Lynne T1 Noninvasive Detection of Genomic Imbalances in HL Is Promising JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 55 SP 18 OP 19 DO 10.1177/1559897715570844 UL http://mdc.sagepub.com/content/14/55/18.abstract AB Noninvasive massive parallel sequencing of circulating cell-free DNA allows the identification of genomic imbalances in Hodgkin/Reed-Sternberg cells in early and advanced stage NSHL. This discovery may facilitate the development of predictive biomarkers and monitoring early disease response to therapy. These issues will be investigated in the context of clinical trials.