RT Journal Article SR Electronic A1 Lederman, Lynne T1 Benefit of Extended Anticoagulation After Unprovoked PE Lost After Treatment Discontinuation JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 55 SP 11 OP 11 DO 10.1177/1559897714568629 UL http://mdc.sagepub.com/content/14/55/11.abstract AB After a first episode of unprovoked pulmonary embolism initially treated during 6 months, extending anticoagulant therapy with warfarin for an additional 18 months significantly reduces the risk of recurrent venous thromboembolism. However, by 2 years after therapy is discontinued, the risk of recurrent thrombolic events is no different between the warfarin treatment group and the placebo group.