RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Th17-Prone CD146+CCR5+ T-Cell Population Is an Early Marker of Intestinal GVHD
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 55
SP 8
OP 8
DO 10.1177/1559897714568635
UL http://mdc.sagepub.com/content/14/55/8.1.abstract
AB Allogeneic hematopoietic stem-cell transplantation is a promising treatment approach in patients who require hematopoietic stem cell transplantation. A significant drawback is the occurrence of acute graft-vs-host disease, which occurs when newly transplanted donor lymphocytes attack the transplant recipient's body. The discovery of the Th17-prone CD146+CCR5+ T-cell population may be an early biomarker for intestinal graft-vs-host disease leading to more specific preventions strategies.