RT Journal Article
SR Electronic
A1 Lederman, Lynne
T1 Most Genes Associated With Increased Risk of BC Remain Poorly Characterized
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 56
SP 28
OP 29
DO 10.1177/1559897715572122
UL http://mdc.sagepub.com/content/14/56/28.abstract
AB BRCA1 and BRCA2 mutations are clearly associated with an increased risk of breast cancer; increased screening and surgery are important for management, but the role of chemoprevention is unclear. Other genes contribute to breast cancer risk, although most remain unidentified. Enrollment of patients into screening and prevention trials is needed to advance the field.