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- Figure 1.
Functional and Therapeutic Map of Gene Mutations to Guide Drug Development
HER2, human epidermal growth factor receptor 2; PI3K, phosphatidylinositol-3-kinase; RTK, receptor tyrosine kinase.
Adapted from Cancer Discovery, Copyright 2013;3:27–34, Ellis MJ et al. The Genomic Landscape of Breast Cancer as a Therapeutic Roadmap. With permission from AACR.
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Harnessing Genomics and Molecular Profiling in ER-Positive BC for New Therapies
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