Figure 1.
Functional and Therapeutic Map of Gene Mutations to Guide Drug Development
HER2, human epidermal growth factor receptor 2; PI3K, phosphatidylinositol-3-kinase; RTK, receptor tyrosine kinase.
Adapted from Cancer Discovery, Copyright 2013;3:27–34, Ellis MJ et al. The Genomic Landscape of Breast Cancer as a Therapeutic Roadmap. With permission from AACR.