PT  - JOURNAL ARTICLE
AU  - Nichols, Emma Hitt
ED  - Loibl, Sibylle
TI  - Neoadjuvant Chemotherapy in Women 35 and Under
DP  - 2013 Mar 01
TA  - MD Conference Express
PG  - 13--14
VI  - 12
IP  - 20
4099  - http://mdc.sagepub.com/content/12/20/13.short
4100  - http://mdc.sagepub.com/content/12/20/13.full
AB  - Evidence suggests that breast cancer in younger women may be clinically and etiologically distinct from older women [Bleyer A et al. Nat Rev Cancer 2010]. Breast cancer in young women demonstrates a worse prognosis and a more aggressive phenotype, higher proportions of high-grade and later-stage tumors, lower estrogen receptor positivity, and, in some studies, higher expression of human epidermal growth factor receptor 2 [Bleyer A et al. Nat Rev Cancer 2010; Gnerlich JL et al. J Am Coll Surg 2009]. This article presents data on the response to neoadjuvant chemotherapy in women with breast cancer who are aged =35 years compared with older women.