PT  - JOURNAL ARTICLE
AU  - Rizzo, Toni
ED  - Yarnold, John
TI  - The UK START Trials: 10-Year Follow-Up Results
DP  - 2013 Mar 01
TA  - MD Conference Express
PG  - 9--9
VI  - 12
IP  - 20
4099  - http://mdc.sagepub.com/content/12/20/9.1.short
4100  - http://mdc.sagepub.com/content/12/20/9.1.full
AB  - The international standard for radiotherapy after primary surgery for early breast cancer has been a total dose of 50 Gy administered in 25 small daily fractions over 5 weeks. However, the randomized UK Standardisation of Breast Radiotherapy [START] trials indicate that a lower total dose delivered in fewer larger fractions is likely to be safe and effective [START Trialists' Group. Lancet 2008; Lancet Oncol 2008]. This article presents the 10-year follow-up results of the UK START trials, which tested 13- and 15-fraction regimens in women with completely excised early breast cancer (T1–3, N0–1, M0).