RT Journal Article SR Electronic A1 Vinall, Maria T1 Challenge and Strategy of Therapy in Patients with Chronic Atrial Fibrillation JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 3 SP 30 OP 33 DO 10.1177/155989771303018 UL http://mdc.sagepub.com/content/13/3/30.abstract AB Among other topics, this article discusses showing that catheter ablation guided by complex fractionated atrial electrograms (CFAE) is a viable alternative treatment for atrial fibrillation (AF) in the elderly, and reviewed some of these ablation strategies with a focus on 3D automated CFAE-guided right atrium ablation. The article also presents results from a prospective randomized study that assessed the comparative efficacy of a stepwise ablation approach and a simplified approach consisting of two circumferential pulmonary vein antrum isolations and three linear atrial ablations in patients with persistent AF.