PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Nademanee, Koonlawee TI - Challenge and Strategy of Therapy in Patients with Chronic Atrial Fibrillation DP - 2013 Jul 01 TA - MD Conference Express PG - 30--33 VI - 13 IP - 3 4099 - http://mdc.sagepub.com/content/13/3/30.short 4100 - http://mdc.sagepub.com/content/13/3/30.full AB - Among other topics, this article discusses showing that catheter ablation guided by complex fractionated atrial electrograms (CFAE) is a viable alternative treatment for atrial fibrillation (AF) in the elderly, and reviewed some of these ablation strategies with a focus on 3D automated CFAE-guided right atrium ablation. The article also presents results from a prospective randomized study that assessed the comparative efficacy of a stepwise ablation approach and a simplified approach consisting of two circumferential pulmonary vein antrum isolations and three linear atrial ablations in patients with persistent AF.