Summary

Combination treatment of beraprost and sildenafil results in improved 6-minute walk test distance and decreases N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and time to worsening in patients with pulmonary arterial hypertension. This article presents data from the Beraprost Combined Therapy With Sildenafil for Pulmonary Arterial Hypertension study [BEST; ChiCTR-TCC-12002776].