RT Journal Article SR Electronic A1 Vinall, Maria T1 Addition of Spironolactone to Ambrisentan May Be a Novel Treatment Strategy to Improve Outcome in Patients with PAH JF MD Conference Express YR 2013 FD SAGE Publications VO 13 IS 4 SP 15 OP 16 DO 10.1177/155989771304007 UL http://mdc.sagepub.com/content/13/4/15.2.abstract AB This article presents the results of a retrospective study that demonstrated a trend toward additional clinical improvement when spironolactone was added to ambrisentan for the treatment of patients with pulmonary arterial hypertension. This study analyzed data from patients in the double-blind, placebo-controlled Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension studies [ARIES-1 and −2; Galiè N et al. Circulation 2008].