PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Maron, Bradley TI - Addition of Spironolactone to Ambrisentan May Be a Novel Treatment Strategy to Improve Outcome in Patients with PAH DP - 2013 Aug 01 TA - MD Conference Express PG - 15--16 VI - 13 IP - 4 4099 - http://mdc.sagepub.com/content/13/4/15.2.short 4100 - http://mdc.sagepub.com/content/13/4/15.2.full AB - This article presents the results of a retrospective study that demonstrated a trend toward additional clinical improvement when spironolactone was added to ambrisentan for the treatment of patients with pulmonary arterial hypertension. This study analyzed data from patients in the double-blind, placebo-controlled Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension studies [ARIES-1 and −2; Galiè N et al. Circulation 2008].