PT  - JOURNAL ARTICLE
AU  - Rizzo, Toni
ED  - Schiff, Michael
TI  - Abatacept and Adalimumab Equally Effective for Rheumatoid Arthritis
DP  - 2013 Sep 01
TA  - MD Conference Express
PG  - 6--7
VI  - 13
IP  - 8
4099  - http://mdc.sagepub.com/content/13/8/6.short
4100  - http://mdc.sagepub.com/content/13/8/6.full
AB  - To date, few direct comparisons of biologic agents for the treatment of rheumatoid arthritis (RA) have been conducted, resulting in a lack of evidence-based guidance for selection of biologic therapy. The Abatacept Versus Adalimumab Comparison in Biologic-Naïve RA Subjects With Background Methotrexate trial [AMPLE; NCT00929864] was the first powered head-to-head study comparing two biologic disease-modifying antirheumatic drugs, abatacept and adalimumab, with the standard of care, methotrexate. This article discusses Phase 3b of the AMPLE trial.