PT  - JOURNAL ARTICLE
AU  - Cunningham, Muriel
ED  - Siraj, Elias S.
TI  - Insulin Dose Not Linked to Cardiovascular Mortality in the ACCORD Trial
DP  - 2013 Sep 01
TA  - MD Conference Express
PG  - 12--13
VI  - 13
IP  - 11
4099  - http://mdc.sagepub.com/content/13/11/12.short
4100  - http://mdc.sagepub.com/content/13/11/12.full
AB  - Previously published results from the Action to Control Cardiovascular Risk in Diabetes study [ACCORD; ACCORD Study Group. N Engl J Med 2008] showed an increased risk of all-cause and cardiovascular (CV) mortality in the intensive control group (HbA1C target, <6.0%) compared with the less intensive group (HbA1C target, 7.0% to 7.9%). Several post hoc analyses did not find a conclusive link between the ACCORD results and factors such as hypoglycemia, low HbA1C, the rapid decline in HbA1C during the first year of the study, weight gain, and specific medication use.