Mendelian Randomization as a Promising Approach to Define Which Biomarkers are Causal for Myocardial Infarction

Article Figures & Data

Figures

  • Figure 1.

    Lipoprotein Association With Risk of CHD

    Reproduced from The Emerging Risk Factors Collaboration. Major Lipids, Apolipoproteins, and Risk of Vascular Disease. J JAMA 2009;302(18):1993–2000. With permission from the American Medical Association.
  • Figure 2.

    Comparison of a Randomized, Controlled Trial to Mendelian Randomization

    CV=cardiovascular.Reproduced from Hingorani A, Humphries S. Nature's randomised trials. Lancet 2005;366(9501):1906–1908. With permission from Elsevier.
  • Figure 3.

    Schematic of Mendelian Randomization for the LDL Biomarker

    CHD=coronary heart disease; LDL-C=low-density lipoprotein cholesterol; MI=myocardial infarction.Reproduced with permission from S Kathiresan, MD.
  • MANY THANKS The editors would like to thank the many members of the XXIV Congress of the ISTH presenting faculty who generously gave their time to ensure the accuracy and quality of the articles in this publication.