RT Journal Article
SR Electronic
A1 Parry, Nicola
T1 Updated Guidelines for Classifying Gastroenteropancreatic Neuroendocrine Neoplasms
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 10
SP 8
OP 9
DO 10.1177/155989771310002
UL http://mdc.sagepub.com/content/13/10/8.abstract
AB This article discusses the nomenclature of neuroendocrine tumors (NETs), according to the updated 2010 World Health Organization (WHO) classification. This scheme classifies NETs based on prognostication by their proliferative activities, with respect to mitotic rate and Ki-67 labeling index. Since this accounts for tumor grading and prognosis, it facilitates development of treatment strategies, with somatostatin receptor 2a-positive tumors in particular demonstrating improved response to therapy with somatostatin analogs.