PT  - JOURNAL ARTICLE
AU  - Parry, Nicola
ED  - Park, Kyong Soo
TI  - PPAR-Mediated Mechanisms of Skeletal Muscle Insulin Resistance
DP  - 2013 Dec 01
TA  - MD Conference Express
PG  - 12--13
VI  - 13
IP  - 16
4099  - http://mdc.sagepub.com/content/13/16/12.short
4100  - http://mdc.sagepub.com/content/13/16/12.full
AB  - Skeletal muscle is the major site for insulin-dependent glucose utilization, and insulin resistance in skeletal muscle is thought to be integral in the pathogenesis of type 2 diabetes mellitus (T2DM). This article discusses some emerging insights into the molecular basis of skeletal muscle insulin resistance, highlighting the role of peroxisome proliferator activated receptor-gamma (PPAR-?), a nuclear transcription factor.