<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cunningham, Muriel</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Giugliano, Robert</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Edoxaban Noninferior to Warfarin in the ENGAGE AF-TIMI 48 Trial</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2013</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2013-12-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">24-25</style></pages><abstract><style  face="normal" font="default" size="100%">Warfarin is widely used for stroke prevention in patients with atrial fibrillation (AF) but novel oral anticoagulants have been developed that may be just as effective [Dogliotti A et al. Clin Cardiol 2013]. Edoxaban is a direct oral factor Xa inhibitor administered once daily with a rapid onset of action. Warfarin and two doses of edoxaban were compared in the Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation — Thrombolysis in Myocardial Infarction 48 study [ENGAGE AF-TIMI 48; Giugliano RP et al. N Engl J Med 2013].</style></abstract><number><style face="normal" font="default" size="100%">20</style></number><volume><style face="normal" font="default" size="100%">13</style></volume></record></records></xml>