PT - JOURNAL ARTICLE AU - Buckley, Rita ED - Bartko, D. TI - RIS with Dissemination on MRI DP - 2012 May 01 TA - MD Conference Express PG - 9--9 VI - 12 IP - 2 4099 - http://mdc.sagepub.com/content/12/2/9.1.short 4100 - http://mdc.sagepub.com/content/12/2/9.1.full AB - Although disease-modifying therapies work best when given early in MS, the decision to proactively treat patients with radiologically isolated syndrome (RIS) is countered by the increasing risks associated with disease-modifying therapies as well as the uncertain prognostic outcome of RIS [Spain R, Bourdette D. Curr Neurol Neurosci Rep 2011].