TJC=tender joint count; SJC=swollen joint count; TCZ=tocilizumab; ADA=adalimumab; LOCF used for TJC and SJC; ESR and Patient's Global Assessment of Disease Activity VAS; If ESR=0 then ESR=1 is substituted into the DAS28 calculation to enable a non-missing DAS28.Reproduced with permission from C. Gabay, MD.