PT  - JOURNAL ARTICLE
AU  - Vinall, Phil
ED  - Knop, Filip K.
TI  - GLP-1 Receptor Agonists and DPP-4 Inhibitors
DP  - 2012 Sep 01
TA  - MD Conference Express
PG  - 24--26
VI  - 12
IP  - 10
4099  - http://mdc.sagepub.com/content/12/10/24.short
4100  - http://mdc.sagepub.com/content/12/10/24.full
AB  - Incretins are hormones that stimulate insulin secretion in response to meals. Glucagon-like peptide-1 (GLP-1), an incretin secreted by enteroendocrine L-cells, stimulates insulin release, suppresses glucagon secretion, and reduces appetite, leading to the lowering of blood glucose. This article presents an overview of incretin-based therapies, and discussed the differences between the GLP-1RAs, as well as between dipeptidyl peptidase-4 inhibitors.