PT - JOURNAL ARTICLE AU - Rizzo, Toni ED - Simon, Daniel I. TI - Inflammation and Vascular Injury DP - 2012 Oct 01 TA - MD Conference Express PG - 17--18 VI - 12 IP - 3 4099 - http://mdc.sagepub.com/content/12/3/17.short 4100 - http://mdc.sagepub.com/content/12/3/17.full AB - The focus this article is on a class of leukocyte adhesion molecules, leukocyte β2-integrins, among which Mac-1 (aMb2, CD11b/CD18) is the most common integrin on neutrophils. The leukocyte Mac-1 receptor interacts with the glyocoprotein Iba (GPIba) receptor on platelets, thereby regulating pro-inflammatory and pro-thrombotic bidirectional signals in both inflammatory cells and platelets.