PT  - JOURNAL ARTICLE
AU  - Rizzo, Toni
ED  - Oyama, Junichi
TI  - Incretins in Cardiovascular Disease
DP  - 2012 Oct 01
TA  - MD Conference Express
PG  - 8--8
VI  - 12
IP  - 3
4099  - http://mdc.sagepub.com/content/12/3/8.1.short
4100  - http://mdc.sagepub.com/content/12/3/8.1.full
AB  - This article discusses the potential benefits of incretin therapies in patients with cardiovascular disease. The 2 main incretin hormones are glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide. GLP-1 exerts beneficial effects on myocardial and endothelial function by inhibiting upregulation of reactive oxygen species and vascular cell adhesion molecule-1 mRNA in endothelial cells.