RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 FAME-Trials Family: Physiology, Decision-Making, and Clinical Outcomes
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 8
SP 8
OP 9
DO 10.1177/155989771208003
UL http://mdc.sagepub.com/content/12/8/8.abstract
AB This article discusses the use of fractional flow reserve (FFR) with angiography for detecting significant coronary artery stenosis. FFR is the only functional index that has been validated against a true gold standard. All studies performed in a wide range of clinical and angiographic conditions found an FFR threshold of 0.75 to 0.80 to detect significant stenosis, with a sensitivity of 90% and specificity of 100% [Pijls NHJ et al. N Engl J Med 1996].