PT  - JOURNAL ARTICLE
AU  - Vinall, Phil
ED  - Hites, Maya
TI  - Standard Dosage Regimens of Broad-Spectrum β-Lactams are Inadequate to Treat “Difficult-to-Treat” Pathogens in Obese Noncritically Ill Patients
DP  - 2012 Dec 01
TA  - MD Conference Express
PG  - 28--28
VI  - 12
IP  - 14
4099  - http://mdc.sagepub.com/content/12/14/28.1.short
4100  - http://mdc.sagepub.com/content/12/14/28.1.full
AB  - Results of a large case series of broad spectrum β-lactam agents in obese noncritically ill patients with infection treated using standard dose regimens showed insufficient measured serum concentrations to treat difficult-to-treat pathogens. This article presents a poster [Hites et al. ICAAC 2012 a-637] that suggested altered pharmacokinetics in obese patients may be responsible.