PT  - JOURNAL ARTICLE
AU  - Vinall, Phil
ED  - Vesikari, Timo
TI  - Effectiveness of the 10-Valent Pneumococcal NTHi Protein D Conjugate Vaccine against AOM
DP  - 2012 Dec 01
TA  - MD Conference Express
PG  - 16--17
VI  - 12
IP  - 14
4099  - http://mdc.sagepub.com/content/12/14/16.short
4100  - http://mdc.sagepub.com/content/12/14/16.full
AB  - Acute otitis media (AOM) is a common medical condition with high incidence in children <5 years of age [Monasta L et al. PLoS One 2012]. Accurate diagnosis is difficult and may partially explain differences in incidence rates in different studies and countries [Toll EC, Nunez DA. J Laryngol Otol 2012]. A trial with the 11-valent predecessor protein D conjugate vaccine demonstrated efficacy against AOM episodes caused by S. pneumoniae and NTHi [Prymula R et al. Lancet 2006]. This article presents preliminary data showing a trend toward positive vaccine effectiveness against AOM episodes for 10-valent pneumococcal nontypeable H. influenzae protein D conjugate vaccine in infants.