PT  - JOURNAL ARTICLE
AU  - Vinall, Phil
ED  - Gurbel, Paul
TI  - First Large-Scale Platelet Function Evaluation in an Acute Coronary Syndrome Trial: The Trilogy ACS-Platelet Function Substudy
DP  - 2012  01
TA  - MD Conference Express
PG  - 14--15
VI  - 12
IP  - 18
4099  - http://mdc.sagepub.com/content/12/18/14.short
4100  - http://mdc.sagepub.com/content/12/18/14.full
AB  - In a platelet function substudy of A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects [TRILOGY ACS; NCT00699998] trial, patients with an acute coronary syndrome treated with prasugrel experienced significantly lower platelet reactivity compared with patients treated with clopidogrel. However, there was no relationship between platelet reactivity and the occurrence of ischemic outcomes, nor were there significant differences in the rates of the composite endpoint of cardiovascular death, myocardial infarction and stroke, or TIMI major bleeding between the 2 treatment groups enrolled in the platelet function substudy.