PT  - JOURNAL ARTICLE
AU  - Vinall, Maria
ED  - Heimans, Lotte
TI  - IMPROVED: Final Study Results of Combination Treatment in Patients with Early RA and UA
DP  - 2012  01
TA  - MD Conference Express
PG  - 17--18
VI  - 12
IP  - 19
4099  - http://mdc.sagepub.com/content/12/19/17.short
4100  - http://mdc.sagepub.com/content/12/19/17.full
AB  - Final results of the Induction Therapy with Methotrexate and Prednisone in Rheumatoid or Very Early Arthritis Disease [IMPROVED] study showed that patients with rheumatoid arthritis and undifferentiated arthritis achieved similarly greater rates of remission after early initial treatment with combination therapy (methotrexate and prednisone). Patients who failed to achieve early remission benefited more when switched to a treatment strategy with adalimumab than with multiple disease modifying antirheumatic drugs, with virtually no radiographic damage progression in all patients.