RT Journal Article SR Electronic A1 Koh, Kwang Kon T1 Multiple Targeted Therapy is Critical for Reducing Cardiometabolic Risk JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 2 SP 16 OP 17 DO 10.1177/155989771102008 UL http://mdc.sagepub.com/content/11/2/16.abstract AB Obesity is associated with a range of adverse metabolic consequences, including endothelial dysfunction, systemic inflammation, and insulin resistance. Therefore, to provide effective protection against the development of atherosclerosis and heart disease, obese patients require combination drug regimens that target several cardiometabolic risk factors.