RT Journal Article
SR Electronic
A1 Jacobson, Anne
T1 Researchers Work to Define Phenotypes of Obstructive Sleep Apnea
JF MD Conference Express
YR 2011
FD SAGE Publications
VO 11
IS 4
SP 16
OP 17
DO 10.1177/155989771104010
UL http://mdc.sagepub.com/content/11/4/16.abstract
AB Obstructive sleep apnea (OSA) is a complex disease that is characterized by the collapse of the pharyngeal airway, resulting in recurrent episodes of airway closure, oxygen desaturation, and disrupted sleep. In recent studies, researchers have sought to define multiple phenotypes on the basis of local and distant anatomy, sleep breathing and arousal patterns, and response to treatment. In this article, experts in sleep-disordered breathing discussed the spectrum of OSA phenotypes and their implications for therapy.